Schizophrenia Research

(Also Known As: Paranoid Schizophrenia Research, Schizophrenic Research, Delusional Research, Psychosis Research)

(Reviewed by: Paul Peterson, Licensed Therapist)

Schizophrenia Related Research


The Schizophrenia Patient Outcomes Research Team (PORT) have developed recommendations on the treatment of schizophrenia based on an exhaustive review of treatment outcomes and literature where they have found substantial evidence of efficacy. They recognized that schizophrenia treatment should not depend mainly on making the diagnosis, but it will also depend on the variety of factors such as the presence of other medical and psychiatric conditions as well as social and personal circumstances and individual variations. The treatment recommendations are based on well-controlled research by which the efficiencies of the recommended treatments have been carefully studied. The following are the recommended treatments for schizophrenia: 11

  • Antipsychotic agents and adjunctive pharmacotherapies
  • Electroconvulsive therapy
  • Psychological interventions
  • Family interventions
  • Vocational rehabilitations
  • Assertive community treatment and intensive case management


The Department of Psychiatry of the Columbia University of New York State Psychiatric Institute, New York conducted a study that examined schizophrenics with good premorbid adjustments on their illness and found they are more vulnerable to being demoralized, which increases their suicidal tendencies. Using the Diagnostic Interview for Genetic Studies and the Premorbid Adjustment Scale they assessed the depressive symptoms occurring in schizophrenia in relation to the suicidal behavior of the patients. Their study concluded that those who attempt suicides have higher level of depressions during the course of their disorder. 12


Three major proteins have been linked as the possible genetic cause for schizophrenia based on the research conducted by the team of NARSAD investigators. The molecular circuitry associated with schizophrenia includes three proteins namely DISC1 (disrupted in schizophrenia 1), BBS4 and PCM1. These three proteins are binding together and the failure of one protein to act results in abnormal brain development, knowing that the three proteins need to work synergistically together for normal brain development. 13

Could You Have Schizophrenia?

Schizophrenia Topics

Related Conditions

Bipolar Disorder – Psychosis, Hallucinations, Delusions, Suicide, Hypomania, Hypermania
Borderline Personality Disorder – Mood Variations/Changes, Unstable Interpersonal Relationships, Dissociation
Schizotypal Personality Disorder – Social Isolation, Odd Behavior, Unconventional Beliefs, Paranoia, Social Anxiety