Oppositional Defiant Disorder Research

(Also Known As: ODD Research, Adhd Research, Defiant Research, Oppositional Research, Bi-Polar Research, Explosive Disorder Research)

(Reviewed by: Paul Peterson, Licensed Therapist)

Oppositional Defiant Disorder Related Research


Recent studies showed possible effects of certain medications on oppositional defiant disorder. 8 The medicine research is mainly preliminary and is suggestive that there could be some medicines that can help in the treatment of oppositional defiant disorder.

Ritalin is one of the considered medicines in the treatment of oppositional defiant disorder and ADHD. When Ritalin was used to treat children with oppositional disorder about 90% of them no longer have the condition by the end of the study. Some children however dropped from the research study due to non-compliance with the treatment regimen, but despite this treatment failure the study still showed 75% success rate.

Strattera is another drug being studied for the treatment of oppositional defiant disorder. One study outcome its failure while another study showed that Strettera helped in the improvement of the condition.

Another Canadian study was conducted that studied Risperdal in treating the aggressive behavior in children who have below normal intelligence, without consideration whether there is the presence of ADHD. Divalproex is another mood stabilizer which is considered to be helpful in oppositional defiant disorder owing to its 80% effectiveness in controlling explosive behavior in children. Moreover a pilot study is being conducted on the use of Omega 3 oils and Vitamin E in helping the problem behavior in children.


In research conducted by the Neuropediatric Department of Sabadell Hospital in Barcelona, Spain, they reviewed the concept of the oppositional defiant disorder and conduct disorder with a theoretical foundation that there are two behavioral interventions, namely the cognitive and behaviorist models, that help in the treatment of the behavior seen in both conditions. They also outlined the different pharmacological options to facilitate the therapeutic process. The research’s conclusion showed that emphasis should be placed on psychological intervention as the best therapeutic approach to oppositional defiant disorder and therapy should be based on the guidelines that are designed to orient the school and the family of the patient. The study further revealed that the behavioral intervention is not founded from general education level but instead rests on the knowledge of the dysfunctional cognitive characteristic of the child. Medication should also complement the behavioral treatment in severe cases. 9


The Division of Child and Adolescent Psychiatry of University of Minnesota aimed to conduct a research to examine the developmental progression of oppositional defiant disorder (ODD) in children with attention deficit hyperactivity disorder (ADHD) and with persistence and desistence of oppositional defiance disorder on the emergence of conduct disorder (CD). The outcome of the study showed that in children with ODD and ADHD only 2.3% developed CD at follow-up. Over time the study showed there is 57% of ODD persistence and 43% of ODD desistance. Furthermore, the study also found negative parenting results in persistence of ODD. The research concluded that there is little evidence to show that ODD is a precursor to CD, but upon the diagnosis of CD the condition already has an associated condition of ODD. The smaller subgroup of children with ADHD, the symptoms showed by ODD are unstable with transient developmental perturbations with less significance in prognosis. In the larger subgroups of children with ADHD, the symptoms of ODD usually persist in the adolescent years and adverse parenting practices are highly associated. 10

Could You Have Oppositional Defiant Disorder?

Oppositional Defiant Disorder Topics

Related Conditions

Antisocial Personality Disorder – disregard of rights of others, deceitful, manipulative, antisocial
Anxiety Disorder NOS – uneasiness, extreme worry, irrational fear, emotional imbalance, moody
Attention Deficit Hyperactivity Disorder – neurobehavioral disorder, impulsiveness, hyperactive, attention deficit, inattention, developmental disorder, inadequate coping mechanism
Bipolar Disorder – hypermania, hypomania, mood disorder, psychosis, depression, anxiety, suicidal tendency, mixed episodes of mania and depression